The photodynamic activity occurring through the lysosome photo-damage is effective in terms of triggered synergic effectswhich can avoid chemo-resistance pathways. The potential photodynamic activity of twofluorescent lysosome-specific probes was studied providing their interaction with human serum albumin, demonstrating their in vitro generation of singlet oxygen and investigating the resulted photo-toxic effect in human cancer cells..

Photodynamic activity of thiophene-derived lysosome-specific dyes

BALDASSARRE, FRANCESCA
Primo
;
TEPORE, Antonio
Penultimo
;
CICCARELLA, Giuseppe
Ultimo
2016

Abstract

The photodynamic activity occurring through the lysosome photo-damage is effective in terms of triggered synergic effectswhich can avoid chemo-resistance pathways. The potential photodynamic activity of twofluorescent lysosome-specific probes was studied providing their interaction with human serum albumin, demonstrating their in vitro generation of singlet oxygen and investigating the resulted photo-toxic effect in human cancer cells..
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11587/407531
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