The article proposes an Equivalent Single Layer (ESL) formulation for the linear static analysis of arbitrarily-shaped shell structures subjected to general surface loads and boundary conditions. A parametrization of the physical domain is provided by employing a set of curvilinear principal coordinates. The generalized blending methodology accounts for a distortion of the structure so that disparate geometries can be considered. Each layer of the stacking sequence has an arbitrary orientation and is modelled as a generally anisotropic continuum. In addition, re-entrant auxetic three-dimensional honeycomb cells with soft-core behaviour are considered in the model. The unknown variables are described employing a generalized displacement field and pre-determined through-the-thickness functions assessed in a unified formulation. Then, a weak assessment of the structural problem accounts for shape functions defined with an isogeometric approach starting from the computational grid. A generalized methodology has been proposed to define two-dimensional distributions of static surface loads. In the same way, boundary conditions with three-dimensional features are implemented along the shell edges employing linear springs. The fundamental relations are obtained from the stationary configuration of the total potential energy, and they are numerically tackled by employing the Generalized Differential Quadrature (GDQ) method, accounting for nonuniform computational grids. In the post-processing stage, an equilibrium-based recovery procedure allows the determination of the three-dimensional dispersion of the kinematic and static quantities. Some case studies have been presented, and a successful benchmark of different structural responses has been performed with respect to various refined theories.
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