Gut-on-chip (GOC) platforms are microfluidic devices with micro-chambers and channels to support and control media volumes and flow through a living cell culture generally seeded on membranes that create 2 chambers (lower and upper). This technology mimics the physiological architecture and function as well as the pathological states of human epithelial organs. Several models reproducing human GOC have underlined their potential value as for disease and drug screening modelling.

Technology and application of gut-on-chip. Gut epithelial mimicking in Integrated sensor platforms

Lucia Giampetruzzi;Amilcare Barca;Tiziano Verri;
2019-01-01

Abstract

Gut-on-chip (GOC) platforms are microfluidic devices with micro-chambers and channels to support and control media volumes and flow through a living cell culture generally seeded on membranes that create 2 chambers (lower and upper). This technology mimics the physiological architecture and function as well as the pathological states of human epithelial organs. Several models reproducing human GOC have underlined their potential value as for disease and drug screening modelling.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11587/442918
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