Ni cyanide catalyzes the carbonylation of vinyl bromides and chlorides to α,β-unsatd. acids. Thus, treatment of trans-β-bromostyrene with 6N NaOH, toluene, and catalytic quantities of cetyltrimethylammonium bromide and Ni(CN)2 for 2.5 h at 95° and one atm of CO afforded 75% trans-cinnamic acid.
Stereospecific nickel- and phase-transfer-catalyzed carbonylation of vinyl bromides and chlorides
VASAPOLLO, Giuseppe
1989-01-01
Abstract
Ni cyanide catalyzes the carbonylation of vinyl bromides and chlorides to α,β-unsatd. acids. Thus, treatment of trans-β-bromostyrene with 6N NaOH, toluene, and catalytic quantities of cetyltrimethylammonium bromide and Ni(CN)2 for 2.5 h at 95° and one atm of CO afforded 75% trans-cinnamic acid.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
