A serological survey was performed to determine the prevalence of antibodies against human bocavirus in Apulian population. Anti-hBoV IgG antibodies were analyzed in 1,206 inhabitants (Age range: 1 month-84 years) using a standardized ELISA test based on the use of recombinant hBoV VP2 virus-like particles. In total, 1,075 (89.1%) of 1,206 participants (mean age 32±24.8 yrs) displayed anti-hBoV-IgG. The seroprevalence increased significantly (p<0.0001) in children from 2-4 yrs (64.2%) to 5-9 yrs (96.4%). A similar trend was observed in both males and females. In conclusion, our results show that hBoV infection is common in population, especially in children.
Seroepidemiology of human bocavirus in Apulia, Italy
GUIDO, Marcello;DE DONNO, Maria Antonella;QUATTROCCHI, MANUELA;
2012-01-01
Abstract
A serological survey was performed to determine the prevalence of antibodies against human bocavirus in Apulian population. Anti-hBoV IgG antibodies were analyzed in 1,206 inhabitants (Age range: 1 month-84 years) using a standardized ELISA test based on the use of recombinant hBoV VP2 virus-like particles. In total, 1,075 (89.1%) of 1,206 participants (mean age 32±24.8 yrs) displayed anti-hBoV-IgG. The seroprevalence increased significantly (p<0.0001) in children from 2-4 yrs (64.2%) to 5-9 yrs (96.4%). A similar trend was observed in both males and females. In conclusion, our results show that hBoV infection is common in population, especially in children.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
