The inter- and intra-mol. regioselective cyclocarbonylative coupling of 2-aminophenol and 2-aminothiophenol with various allyl halides was achieved in the presence of a catalytic amt. of palladium acetate and 1,4-bis(diphenylphosphino)butane to afford N-aryl-2-pyrrolidinones in 47-65% yields. Other aminophenol derivs. have also been used and gave good yields of N-aryl-2-pyrrolidinones.
Palladium(II) and bidentate phosphine-catalyzed selective synthesis of N-aryl-2-pyrrolidinones via cyclocarbonylative coupling of 2-aminophenol and 2-aminothiophenol
MELE, Giuseppe Agostino;CICCARELLA, Giuseppe;VASAPOLLO, Giuseppe
2002-01-01
Abstract
The inter- and intra-mol. regioselective cyclocarbonylative coupling of 2-aminophenol and 2-aminothiophenol with various allyl halides was achieved in the presence of a catalytic amt. of palladium acetate and 1,4-bis(diphenylphosphino)butane to afford N-aryl-2-pyrrolidinones in 47-65% yields. Other aminophenol derivs. have also been used and gave good yields of N-aryl-2-pyrrolidinones.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
