In the framework of the SPOT-NOSED European project, nanoscale sensing elements bearing olfactory receptors and grafted onto functionalized gold substrates are used as odorant detectors to develop a new concept of nanobioelectronic nose, through sensitive impedancemetric measurement of single receptor conformational change upon odorant ligand binding, with a better specificity and lower detection thresholds than traditional physical sensors.
Nanobiosensors based on individual olfactory receptors
ALFINITO, ELEONORA;PENNETTA, Cecilia;REGGIANI, Lino;
2008-01-01
Abstract
In the framework of the SPOT-NOSED European project, nanoscale sensing elements bearing olfactory receptors and grafted onto functionalized gold substrates are used as odorant detectors to develop a new concept of nanobioelectronic nose, through sensitive impedancemetric measurement of single receptor conformational change upon odorant ligand binding, with a better specificity and lower detection thresholds than traditional physical sensors.File in questo prodotto:
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